魏  洁

职称：副教授

性别：女

毕业院校：武汉大学

学历：博士研究生

学位：博士

所在单位：海洋食品与生物工程学院

入职时间：2020-07

学科：食品科学与工程、生物工程

办公地点：灿英楼416

通讯地址：厦门市集美区印斗路43号

E-mail: jiewei@jmu.edu.cn

个人简介

理学博士，副教授，硕士生导师，福建省高层次人才，厦门市高层次人才。主要从事核酸纳米技术在食品安全检测、生物传感等方面的研究。近年来累计发表SCI论文50余篇，其中以第一作者/通讯作者在Angewandte Chemie International Edition、Nucleic Acids Research、Chemical Science、CCS Chemistry、Journal of Agricultural and Food Chemistry、Food Chemistry等期刊共发表学术论文16篇，SCI引用超过100次的论文2篇，先后被评为ESI高引论文2篇。申请专利6项，已获授权2项。主持国家自然科学基金青年基金项目、福建省自然科学基金青年项目、福建省教育厅面上项目，参与多项国家级项目。

教育经历

[1] 2016.09-2020.06 武汉大学，分析化学，博士

[2] 2014.09-2016.06 武汉大学，化学工程，硕士

[3] 2010.09-2014.06 湖北师范大学，化学，学士

工作经历

[1] 2023.09-至今集美大学，海洋食品与生物工程学院，副教授

[2] 2020.07-2023.08 集美大学，海洋食品与生物工程学院，讲师

研究方向

[1] 食品安全检测技术

[2] 生物传感

[3] 核酸纳米技术

代表性科研项目

[1] 国家自然科学基金青年项目，交叉催化型核酸扩增反应用于miRNA高灵敏检测和基因调控的研究，22204057，2023.01-2025.12，主持

[2] 福建省自然科学基金青年项目，基于自催化核酸扩增反应用于miRNA检测和基因调控，2021J05162，2021.08-2024.08，主持

[3] 福建省教育厅-面上，核酸恒温扩增新方法的构建及在抗生素残留检测中的应用，JAT200278，2021.01-2023.12，主持

[4] 国家自然科学基金委员会面上项目，水产品中痕量化学污染物的aTFs/UCNPs柔性纳米传感快速高灵敏检测机理研究，32272414，2023.01-2026.12，参与

[5] 国家自然科学基金委员会面上项目，多酸型线粒体生物合成调控剂的精准合成与性能，22271119，2023.01-2026.12，参与

代表性科研论文

[1] Qingyang Si, Yumeng Li, Ziling Huang, Chuanyi Liu, Tianhui Jiao, Qingmin Chen, Xiaomei Chen, Quansheng Chen*, Jie Wei*. Isothermal reciprocal catalytic DNA circuit for sensitive analysis of kanamycin, Journal of Agricultural and Food Chemistry, 2024, 72, 6754-6761.

[2] Ziling Huang, Chuanyi Liu, Zhigang Li, Qingmin Chen, Dong Li, Xiaomei Chen, Quansheng Chen, Jie Wei*. Multiple DNA cycle amplification for highly efficient detection of mercury pollution in food, Food Chemistry, 2024, 460, 140714.

[3] Chuanyi Liu, Ziling Huang, Zhigang Li, Xiaojiao Dai, Qingmin Chen, Min Chen, Yi Xu, Xiaomei Chen, Fuan Wang, Quansheng Chen*, Jie Wei*. A self-sustainable DNA amplification circuit for sensitive microRNA imaging, Analytica Chimica Acta, 2025, 1343, 343689.

[4] Xiaojiao Dai, Ziling Huang, Chuanyi Liu, Zhigang Li, Qingmin Chen, Yi Xu, Xiaomei Chen, Quansheng Chen*, Jie Wei*. Engineering of a DNAzyme-based aptasensor for highly efficient ATP detection and oyster freshness evaluation. Journal of Food Composition and Analysis, 2025, 139, 107176.

[5] Qingyang Si†, Ziling Huang†, Xiaojiao Dai, Qingmin Chen, Tianhui Jiao, Xiaomei Chen, Quansheng Chen, Jie Wei*. A highly efficient homogeneous electrochemiluminescence aptasensor for amplified analysis of Ochratoxin A, Sensors and Actuators B: Chemical, 2024, 418, 136236.

[6] Yumeng Li, Qingyang Si, Chuanyi Liu, Ziling Huang, Qingmin Chen, Tianhui Jiao, Xiaomei Chen, Quansheng Chen*, Jie Wei*. Construction of a self-sufficient DNA circuit for amplified detection of kanamycin, Food Chemistry, 2023, 418, 136048.

[7] Qingyang Si†, Yumeng Li†, Ziling Huang, Chuanyi Liu, Xiaomei Chen, Jie Wei*, Fuan Wang*. Construction of a simple dual-mode ATP-sensing system for reliable fish freshness evaluation, Analytica Chimica Acta, 2023, 1252, 341048.

[8] Yumeng Li†, Chuanyi Liu†, Qingyang Si, Tianhui Jiao, Qingmin Chen, Xiaomei Chen, Quansheng Chen*, Jie Wei*. Construction of an autocatalysis-driven DNA circuit for highly efficient detection of H5N1 oligonucleotide, Sensors and Actuators B: Chemical, 2023, 394, 134393.

[9] Mingming Yin, Weijie Wang, Jie Wei*, Xiaomei Chen*, Quansheng Chen*, Xi Chen, Munetaka Oyama. Novel dual-emissive fluorescent immunoassay for synchronous monitoring of okadaic acid and saxitoxin in shellfish, Food Chemistry, 2022, 368, 130856.

[10] Jie Wei†, Mengdi Yu†, Kaiyue Tan, Jinhua Shang, Shizhen He, Chenxia Xie, Xiaoqing Liu*, Fuan Wang*. Tailoring a Minimal Self-Replicate DNA Circuit for Highly Efficient Intracellular Imaging of microRNA, Small, 2023, 19, 2207961.

[11] Jie Wei†, Jinhua Shang†, Shizhen He, Yu Ouyang, Itamar Willner*, Fuan Wang*. Construction of a Homogeneous Enzyme-Free Autocatalytic Nucleic Acid Machinery for High-Performance Intracellular Imaging of MicroRNA, CCS Chemistry, 2022, 11, 3549-3562.

[12] Jie Wei*, Yumeng Li, Qingyang Si, Qiao Xiao, Qingmin Chen, Tianhui Jiao, Quansheng Chen*, Xiaomei Chen*. Hemin/G-quadruplex based electrochemical sensor for highly sensitive detection of ATP in fish, Journal of Electroanalytical Chemistry, 2022, 916, 116374.

[13] Jie Wei, Huimin Wang, Qiong Wu, Xue Gong, Kang Ma, Xiaoqing Liu, Fuan Wang*. A Smart, Autocatalytic, DNAzyme Biocircuit for in Vivo, Amplified, MicroRNA Imaging. Angewandte Chemie International Edition, 2020, 59, 5965-5971. (Hot Paper)

[14] Jie Wei, Huimin Wang, Xue Gong, Qing Wang, Hong Wang, Yangjie Zhou, Fuan Wang*. A Proteinase-Free DNA Replication Machinery for in Vitro and in Vivo Amplified MicroRNA Imaging. Nucleic Acids Research, 2020, 48, e60.

[15] Jie Wei, Xue Gong, Qing Wang, Min Pan, Xiaoqing Liu, Jing Liu, Fan Xia, Fuan Wang*. Construction of an Autonomously Concatenated Hybridization Chain Reaction for Signal Amplification and Intracellular Imaging. Chemical Science, 2018, 9, 52-61. (封面文章)

代表性专利

 [1] 魏洁，李志刚，司庆洋，戴小娇，基于高效均相电致化学发光适配体传感器的OTA分析方法。申请号：CN202410724534.2

[2] 魏洁，黄子泠，戴小娇，刘传艺，李志刚，司庆洋，一种基于恒温自催化CDA-RCA扩增反应的Hg²⁺检测方法及应用。申请号：CN202410677539.4

[3] 魏洁，司庆洋，黄子泠，刘传艺，陈晓梅，陈全胜，一种基于恒温RCD的检测方法及检测试剂盒。申请号：202311493546.0

[4] 魏洁，李渝萌，陈晓梅，一种基于自驱动杂交链式反应的卡那霉素分析方法。申请号：202310059818X

[5] 王富安，魏洁，一种基于级联杂交链式反应的核酸分析方法。专利号：ZL201710937113.8

[6] 王富安，魏洁，李丰哲，一种基于恒温交叉催化核酸酶反应的核酸分析方法。专利号：ZL201911291884.X