刘翼翔

职称：

教授、博士生导师

毕业院校：

中国农业大学

学位：

博士学位

所在单位：

海洋食品与生物工程学院

学科：

食品科学与工程、生物工程

办公地点：

灿英楼517

通讯地址：

福建省厦门市集美区印斗路43号

E-mail:

lyxjmu@jmu.edu.cn

lyxjmu@163.com

联系电话：

18050015585

个人简介

刘翼翔，教授，博士生导师，福建省“杰出青年”科学基金获得者，美国田纳西大学访问学者，集美大学青年拔尖人才，福建省高层次人才。主持国家自然科学基金面上项目、国家重点研发计划项目子课题、福建省“杰出青年”科学基金、福建省自然科学基金面上项目等科研项目20多项，参与国家发改委重大平台项目、国家重点研发项目课题、国家自然科学基金等科研项目10余项。在Trends Food Sci. Tech.、Food Hydrocolloid.、Crit. Rev. Food Sci. Nutr.、J. Agr. Food Chem.、Food Chem.、Carbohyd. Polym.等学术期刊上发表研究论文100多篇，其中以第一/通讯作者发表研究论文80多篇（IF > 10.0的SCI论文12篇，ESI高被引论文5篇）；获得国家发明专利授权22项，实现成果转让11项；获得中国商业联合会科学技术进步奖一等奖1项（排名第一），参编学术专著2部，参与制定国家标准1项。Pathogens等学术期刊客座编辑，Crit. Rev. Food Sci. Nutr.、J. Agr. Food Chem.、Food Funct.、Food Chem.、Mar. Drugs等学术期刊审稿人，中国食品科学技术学会休闲食品分会理事、中国食品科学技术学会全谷物分会专家委员、全谷物食品产学研联盟理事、科技部专家库成员、中国国际工程咨询公司专家库成员、福建省食品安全风险评估与营养健康专家委员会成员、福建省科技厅/厦门市科技局专家库成员。

主要研究方向

1．肠道健康营养调控与理论创新

2．膳食营养成分稳定与调控新技术

3．天然活性产物开发与营养产品研制

教育与工作经历

2008.7-2012.6：中国农业大学，食品科学与营养工程学院，博士学位

2012.7-至今：集美大学，海洋食品与生物工程学院，讲师、副教授、教授

社会兼职

中国食品科学技术学会休闲食品分会理事、中国食品科学技术学会全谷物分会专家委员、全谷物食品产学研联盟理事、科技部专家库成员、中国国际工程咨询公司专家库成员、福建省食品安全风险评估与营养健康专家委员会成员、福建省科技厅/厦门市科技局/厦门医学会专家库成员、厦门市食品行业协会会员，Critical Reviews in Food Science and Nutrition、Food Hydrocolloids、Journal of Agricultural and Food Chemistry、Food Chemistry、Food & Function等学术期刊审稿人。

代表性科研项目（限5项）

1. 国家自然科学基金面上项目，32372256，2024-2027，主持.

2. 国家重点研发计划子课题，2022YFF1100102-5，2022-2026，主持.

3. 国家重点研发计划子课题，2019YFC1605003-3，2019-2022，主持.

4. 福建省“杰出青年”科学基金，2020J06024，2020-2023，主持.

5. 集美大学青年拔尖人才项目，ZR2020001，2019-2023，主持.

近五年代表性科研论文(*为通讯作者)

1. Liyuan Ma, Weiyi Long, Yixiang Liu*. The fabrication of gastrointestinal pH-responsive sodium alginate surface-modified protein vehicles to improve limonin digestive stability, bioaccessibility and trans-intestinal mucus barrier capacity. Food Hydrocolloids, 2025, 160: 110719. (SCI一区, IF 11.5034) 

2. Yuanjie Guo, Hailan Wang, Liyuan Ma, Zixin Guo, Yixiang Liu*, Jie Zheng*. Construction of glycosylated zein-based colloids to simultaneously improve fucoxanthin's thermal processing adaptability, digestive stability, and oral bioavailability. Colloids and Surfaces B: Biointerfaces, 2025, 245: 114334 (SCI一区, IF 5.3999)

3. Xuan Peng, Dan Li, Yixiang Liu*. Construction of efficient carotenoid delivery vehicles based on the intestinal epithelial transport pathway: Current applications and future trends. Trends in Food Science & Technology, 2024, 147: 104473. (SCI一区, IF 15.2992)

4. Huiying Kuang, Liyuan Ma, Yuanjie Guo, Yixiang Liu*. Chitosan surface-modified bovine serum albumin-oleic acid self-assembled complexes: improving the thermal stability, controlled release and bioaccessibility of fucoxanthin. Food Hydrocolloids, 2024, 151: 109796. (SCI一区, IF 11.5034)

5. Yunjun Liu, Shengnan Wang, Yixiang Liu*. Ultrasound-mediated host-guest self-assembly between different dietary fatty acids and sodium caseinate and their complexes improving the water dispersibility, stability, and bioaccessibility of quercetin. Food Chemistry, 2024, 448: 139054. (SCI一区, IF 9.2306)

6. Huiying Kuang, Xuan Peng, Yixiang Liu*, Dan Li. The pro-absorptive effect of glycosylated zein-fatty acid complexes on fucoxanthin via the lipid transporter protein delivery pathway. Food Chemistry, 2024, 446: 138892. (SCI一区, IF 9.2306)

7. Yunjun Liu, Liyuan Ma, Yuanjie Guo, Huiying Kuang, Yixiang Liu*. Fabricating oleic acid-ovalbumin complexes using an ultrasonic-coupled weakly alkaline pH technique: improving the dispersibility, stability, and bioaccessibility of lutein in water. Food Chemistry, 2024, 435: 137593. (SCI一区, IF 9.2306)

8. Zixin Guo, Yixiang Liu*, Yangchao Luo*. Mechanisms of carotenoid intestinal absorption and the regulation of dietary lipids: lipid transporter-mediated transintestinal epithelial pathways. Critical Reviews in Food Science and Nutrition, 2024, 64: 1791-1816. (SCI一区, IF 11.2078)

9. Yunjun Liu, Yixiang Liu*. Construction of lipid-biomacromolecular compounds for loading and delivery of carotenoids: preparation methods, structural properties, and absorption-enhancing mechanisms. Critical Reviews in Food Science and Nutrition, 2024, 64: 1653-1676. (SCI一区, IF 11.2078)

10. Donghui Li, Yunjun Liu, Yixiang Liu*, Shengnan Wang, Zixin Guo, Jie Li, Yanbo Wang. Effects of different fatty acid ligands on the host-guest interaction of astaxanthin-bovine serum albumin: thermodynamical analysis, binding site identification, and in vivo antioxidant evaluation. Food Hydrocolloids, 2023, 134:108112. (SCI一区, IF 11.5034)

11. Yu Ma, Ming Liu, Donghui Li, Jie Li, Zixin Guo, Yunjun Liu, Shengnan Wan, Yixiang Liu*. Olive oil ameliorates allergic response in murine OVA-induced food allergy by promoting intestinal mucosal immunity. Food Science and Human Wellness, 2023, 12, 784-791. (SCI一区, IF 8.0216)

12. Yuanjie Guo, Yu Ma, Liyuan Ma, Zixin Guo, Yingliang Xiao, Yunjun Liu, Jie Li, Shengnan Wang, Yixiang Liu*. Oleuropein prevents OVA-induced food allergy in mice by enhancing the intestinal epithelial barrier and remodeling the intestinal flora. Molecular Nutrition and Food Research, 2022, 2200455. (SCI二区, IF 6.5749)

13. Jie Li, Chao Zou, Yu Ma, Donghui Li, Zixin Guo, Yunjun Liu, Shengnan Wan, Yixiang Liu*, Yanbo Wang. Synergistic effects of alginate oligosaccharide and cyanidin-3-O-glucoside on the amelioration of intestinal barrier function in mice. Food Science and Human Wellness, 2023, 12: 2276-2285. (SCI一区, IF 8.0216)

14. Donghui Li, Yunjun Liu, Yu Ma, Yixiang Liu*, Shengnan Wang, Zixin Guo, Jie Li, Yanbo Wang, Bin Tan, Ying Wei. Fabricating hydrophilic fatty acid-protein particles to encapsulate fucoxanthin: Fatty acid screening, structural characterization, and thermal stability analysis. Food Chemistry, 2022, 382, 132311. (SCI一区, IF 9.2306)

15. Donghui Li, Yunjun Liu, Yixiang Liu*, Shengnan Wang. Encapsulation of fucoxanthin in fatty acid-bovine serum albumin micelles to improve the stability, bioavailability, and bioefficacy. Colloids and Surfaces B-Biointerfaces, 2022, 220: 112951. (SCI一区, IF 5.9988)

16. Huiying Kuang, Yu Ma, Yixiang Liu*. Protective effect of β-carotene on OVA-induced food allergy in mice by strengthening intestinal epithelial barrier function and regulating intestinal microflora. Food & Function, 2022, 13, 12330 - 12341. (SCI一区, IF 5.396)

17. Shengnan Wang, Yunjun Liu, Yixiang Liu*, Zixin Guo, Jie Li. Improving effect of oleic acid-mediated sodium caseinate-based encapsulation in an ultrasound field on the thermal stability and bioaccessibility of quercetin. Ultrasonics Sonochemistry, 2022, 90: 106169. (SCI一区, IF 9.3366)

18. Bing Han, Yu Ma, Yixiang Liu*. Fucoxanthin prevents the ovalbumin-induced food allergic response by enhancing the intestinal epithelial barrier and regulating the intestinal flora. Journal of Agricultural and Food Chemistry, 2022, 70(33): 10229–10238. (SCI一区, IF 5.8954)

19. Jie Li, Chao Zou and Yixiang Liu*. Amelioration of ovalbumin-induced food allergy in mice by targeted rectal and colonic delivery of cyanidin-3-O-glucoside. Foods, 2022, 11, 1542. (SCI二区, IF 5.5612)

20. Yunjun Liu, Zixin Guo, Shengnan Wang, YiXiang Liu*,Ying Wei. Fucoxanthin pretreatment ameliorates visible light-induced phagocytosis disruption of RPE cells under a lipid-rich envi-ronment via the Nrf2 pathway. Marine Drugs, 2022, 20, 15. (SCI二区, IF 6.0854)

21. Ling Huang, Donghui Li, Yu Ma, Yixiang Liu*, Guangming Liu, Yanbo Wang, Bin Tan. Dietary fatty acid-mediated protein encapsulation simultaneously improving the water-solubility, storage stability, and oral absorption of astaxanthin. Food Hydrocolloids, 2022, 123, 107152. (SCI一区, IF 11.5034)

22. Donghui Li, Qian Zhang, Ling Huang, Zhaohua Chen, Chao Zou, Yu Ma, Min-Jie Cao, Guang-Ming Liu, Yixiang Liu*, Yanbo Wang. Fabricating hydrophilic particles with oleic acid and bovine serum albumin to improve the dispersibility and bioaccessibility of fucoxanthin in water. Food Hydrocolloids, 2021, 118, 106752. (SCI一区, IF 11.5034)

23. Chao Zou, Ling Huang, Donghui Li, Yu Ma, Yixiang Liu*, Yanbo Wang, Min-Jie Cao, Guang-Ming Liu, Lechang Sun. Assembling cyanidin-3-O-glucoside by using low-viscosity alginate to improve its in vitro bioaccessibility and in vivo bioavailability. Food Chemistry, 2021, 355, 129681. (SCI一区, IF 9.2306)

24. Yixiang Liu*, Yu Ma, Zhaohua Chen, Chao Zou, Wenqiang Liu, Lijie Yang*, Linglin Fu, Yanbo Wang, Guang-Ming Liu, Min-Jie Cao. Depolymerized sulfated galactans from Eucheuma serra ameliorate allergic response and intestinal flora in food allergic mouse model. International Journal of Biological Macromolecules, 2021, 166, 977-985. (SCI一区,IF 6.953)

25. Yu Ma, Qian Zhang, Wenqiang Liu, Zhaohua Chen, Chao Zou, Linglin Fu, Yanbo Wang, Yixiang Liu*. Preventive effect of depolymerized sulfated galactans from Eucheuma serra on enterotoxigenic Escherichia coli-caused diarrhea via modulating intestinal flora in mice. Marine Drugs, 2021, 19(2), 80. (SCI二区, IF 6.0854)

26. Yixiang Liu*, Yu Ma, Zhaohua Chen, Donghui Li, Wenqiang Liu, Ling Huang, Chao Zou, Min-Jie Cao, Guang-Ming Liu and Yanbo Wang. Antibacterial activity of sulfated galactans from Eucheuma serra and Gracilari verrucosa against diarrheagenic Escherichia coli via the disruption of the cell membrane structure. Marine Drugs, 2020, 18, 397. (SCI二区, IF 6.0854)

27. Yixiang Liu*, Ling Huang, Donghui Li, Yanbo Wang, Zhaohua Chen, Chao Zou, Wenqiang Liu, Yu Ma, Min-Jie Cao, Guang-Ming Liu. Re-assembled oleic acid-protein complexes as nano-vehicles for astaxanthin: Multispectral analysis and molecular docking. Food Hydrocolloids, 2020, 103, 105689. (SCI一区, IF 11.5034)（高被引论文）

28. Yixiang Liu*, Wenqiang Liu, Yanbo Wang, Yu Ma, Ling Huang, Chao Zou, Donghui Li, Min-Jie Cao and Guang-Ming Liu. Inhibitory effect of depolymerized sulfated galactans from marine red algae on the growth and adhesion of diarrheagenic Escherichia coli. Marine Drugs, 2019, 17,694.(SCI二区, IF 6.0854)

29. Yixiang Liu*, Di Zhang, Guang-Ming Liu, Qingchou Chen, Zhenhua Lu. Ameliorative effect of dieckol-enriched extraction from Laminaria japonica on hepatic steatosis induced by a high-fat diet via β-oxidation pathway in ICR mice. Journal of Functional Foods, 2019, 58, 44-55. (SCI二区, IF 4.451)

30. Yixiang Liu*, Zichun Qiao, Wenqiang Liu, Zhanqun Hou, Di Zhang, Ling Huang, Yaping Zhang*. Oleic acid as a protein ligand improving intestinal absorption and ocular benefit of fucoxanthin in water through protein-based encapsulation. Food & Function, 2019, 10, 4381-4395. (SCI一区, IF 5.396)

授权国家发明专利

1. 一种类胡萝卜素-蛋白微粒及其制备方法和应用, ZL 201910073358.X

2. 一种岩藻黄素-蛋白微粒及其制备方法和应用, ZL 201910080882.X

3. 一种岩藻黄醇-蛋白微粒及其制备方法和应用, ZL 201910081833.8

4. 一种岩藻黄醇-牡蛎肽纳米颗粒及其制备方法和应用, ZL 201910074075.7

5. 一种含岩藻黄醇的视力保护功能食品及其制备方法, ZL 201910074097.3

6. 一种低血糖生成指数面粉及其制备方法和面食, ZL201910188595.0

7. 一种提高视器官抗氧化能力的功能食品及其制备方法, ZL201910080859.0

8. 一种调节肠道菌群和防治食物过敏的组合物及其制备方法,ZL202010095838.9

9. 一种抗过敏硫酸多糖及其制备方法和用途, ZL202010024128.7

10. 一种低黏度岩藻聚糖及其高温高压-酶联耦合制备方法, ZL 201910601993.0

11. 一种冷鲜猪肉纳米保鲜剂及其制备方法和保鲜方法, ZL 2016108670015

12. 一种红外降解海洋硫酸多糖的方法, ZL201610867126.8

13. 一种护肝明目的功能食品, ZL2016103209569

14. 一种降脂保肝的功能食品, ZL201610322166.4

15. 一种高纯度海藻多酚的制备方法, ZL201510648035.0

16. 一种酶法制备褐藻岩藻聚糖与岩藻黄素的方法，ZL201310142757.X

17. 一种岩藻黄素的制备方法及其用途，ZL201410207206.1

18. 一种防治猪腹泻的多糖复合剂及用途，ZL201310376633.8  

19. 一种海藻天然抗氧化剂的制备方法，ZL201410206699.7

20. 一种活性低分子量岩藻聚糖的制备方法及其用途，ZL 201310572750.1  

成果获奖

[1] 刘翼翔,谢荔朋,王翀,王彦波,张迪,吴永沛,刘光明,石正华,吴锦清,章骞,吴国杰.海藻活性产物高效综合开发关键技术与应用.中国商业联合会,全国商业科技进步一等奖，2021.

研究生培养

福建省优秀硕士论文：邹超（2022）、马玉（2023）、李东慧（2023）

集美大学优秀硕士论文：邹超（2021）、马玉（2022）、李东慧（2022）、刘芸君（2023）、况慧颖（2024）

集美大学优秀毕业生：刘文强（2020）

国家奖学金：黄玲（2018）、马玉（2019）、郭紫欣（2022）、刘芸君（2022）

博士研究生升学：李东慧（华中农业大学）、刘芸君（华中农业大学）、马丽媛（西北农林科技大学）、马玉（江南大学）、彭璇（江南大学）、郭缘洁（江南大学）