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曾珺

发布日期:2025-05-22    作者:     来源:     点击:


 

    曾珺

 

职称:教授

 

性别:

 

毕业院校:中国科学院大连化学物理研究所

 

学历:博士研究生

 

学位:理学博士

  

所在单位:食品与生物工程学院

 

入职时间:2016-07-26

  

学科:分析化学

 

办公地点/通讯地址:集美大学食品与生物工程学院灿英309

 

E-mailjunzeng@jmu.edu.cn

个人简介

理学博士,教授,硕士生导师。

已入选福建省高校杰出青年科研人才培育计划”、福建省及厦门市高层次人才。从事高维数据驱动的食品暴露组研究,开展高分辨质谱技术与机器学习相融合的代谢组学/脂质组学新方法开发,并应用于食品危害暴露及营养研究。

近年来先后主持国家自然科学基金青年项目、国家重点研发计划“蓝色粮仓科技创新”重点专项子课题、福建省/厦门市自然科学基金面上/青年项目等;发表SCI论文30余篇,以第一/通讯作者在Nat. Commun.Environ. Sci. Technol.J. Hazard. Mater.Clin. Cancer Res.Food Chem.等发表一区论文10余篇;授权国际/国内专利4件,软件著作权2件。

教育经历

2010.09-2016.07 中国科学院大连化学物理研究所(中科院分离分析化学重点实验室,国家色谱分析研究中心 分析化学博士 (导师:卢佩章院士  许国旺研究员)

2014.11-2014.12  德国图宾根大学医学院(University Hospital TübingenGuest Ph.D. Student

2010.09-2011.06  中国科学技术大学  硕博连读基础课程学习

2006.09-2010.06  中南大学 化学化工学院 应用化学专业 理学学士

工作经历

2016.07-至今 集美大学 食品与生物工程学院 教授(低职高聘)

2024.04-2025.04 亥姆霍兹慕尼黑中心-德国环境健康国家研究中心(Helmholtz Zentrum Munchen)国家公派访问学者

研究方向

1. 高维数据驱动的食品暴露组研究新方法:面向复杂食品/生物体系,开发高分辨质谱技术与机器学习融合的代谢组学新方法

2. 食品暴露组应用研究:食品危害暴露及营养研究

代表性科研项目

1. 国家重点研发计划“蓝色粮仓科技创新”重点专项2019YFD0901704 2019.11-2022.12,子课题负责人

2. 国家自然科学基金青年项目,217070422018.01-2020.12,主持

3. 福建省自然科学基金面上项目,2022J013302022.08-2025.08,主持

4. 厦门市自然科学基金面上项目,3502Z202272082022.07-2025.06,主持

5. 福建省自然科学基金青年创新项目,2019J050962019.07-2022.06,主持

6. 资助省属高校专项项目JK20170262017.09-2020.08,主持

代表性科研论文(第一/通讯作者)

1. Xu, H.#, Jiang, T.H.#, Lin, Y.X.#, Zhang, L.#, Yang, H., Huang, X.Y., Mao, R.D., Yang, Z., Zeng, C.C., Zhao, S., Di, L.J., Zhang, W.B., Zeng, J.*, Cai, Z.W.*, Lin, S.H.*, LipidIN: a comprehensive repository for flash platform-independent annotation and reverse lipidomics. Nat. Commun. 2025, 16, 4566.

2. Li, S.Y.#, Gao, L.H.#, Song, H.Y., Lin, J.Y., Zhang, S.*, Schmitt-Kopplin, P.*, Zeng, J.*, A comprehensive atlas of multi-tissue metabolome and microbiome shifts: exploring obesity and insulin resistance induced by perinatal bisphenol S exposure in high-fat diet-fed offspring. J. Hazard. Mater. 2025, 485, 136895.

3. Zhong, X.L.#, Chen, L.S.#, Xu, H., Jiang, T.H., Hua, Z.Y., Tan, F.C., Mao, X.Y., Fan, Z.Q., Li, Z.W., Zeng, J.*, Lin, S.H.*, Development of a comprehensive computational pipeline for cardiolipin atlas in an intermittent fasting model. Chin. Chem. Lett. 2025, in press. (doi: 10.1016/j.cclet.2025.111027)

4. Gao, L.H.#, Hao, J.W.#, Hua, Z.Y., Zeng, C.C., Li, J.*, Zeng, J.*, A lipidomics atlas tracks alterations associated with deltamethrin-induced developmental neurotoxicity in embryonic zebrafish. J. Proteome Res. 2025, 24(5), 2280-2290.

5. Li, J., Yuan, H.B., Rong, Y.T., Qian, M.C., Liu, F.Q., Hua, J.J., Zhou, Q.H., Deng, Y.L., Zeng, J.*, Jiang, Y.W.*, Lipid metabolic characteristics and marker compounds of ripened Pu-erh tea during pile fermentation revealed by LC-MS-based lipidomics. Food Chem. 2023, 404, 12.

6. Zeng, J. #,*, Hao, J.W. #, Yang, Z.Q. #, Ma, C.Y., Gao, L.H., Chen, Y., Li, G.L., Li, J.*, Anti-Allergic Effect of Dietary Polyphenols Curcumin and Epigallocatechin Gallate via Anti-Degranulation in IgE/Antigen-Stimulated Mast Cell Model: A Lipidomics Perspective. Metabolites 2023, 13(5), 18.

7. Liu, J.W., Gao, J.J., Zhang, E.Q., Jiang, H.R., Li, G.L., Li, J., Zeng, J.*, Wu, D.R.*, Characterization of the sphingolipid profiling of Emiliania huxleyi against virus infection. J OCEANOL LIMNOL 2023, 41(4), 1547-1557.

8. Zeng, J. #,*, Yang, Z.Q. #, Zhong, Y., Zheng, Y.L., Hao, J.W., Luo, G., Yan, Q.P.*, Metabolomics insights into the interaction between Pseudomonas plecoglossicida and Epinephelus coioides. Sci. Rep. 2022. 12(1).

9. Li, J., Hua, J. J., Yuan, H. B., Deng, Y. L., Zhou, Q. H., Yang, Y. Q., Dong, C. W., Zeng, J.*; Jiang, Y. W.*, Investigation on green tea lipids and their metabolic variations during manufacturing by nontargeted lipidomics. Food Chem. 2021, 339, 9.

10. Zeng, J.#,*, Li, J. L.#, Liu, S. S. Y.#, Yang, Z. Q., Zhong, Y., Chen, X. M., Li, G. L., Li, J.*, Lipidome disturbances in preadipocyte differentiation associated with bisphenol A and replacement bisphenol S exposure. Sci. Total Environ. 2021, 753, 10.

11. Zeng, J., Liu, S., Cai, W., Jiang, H., Lu, X., Li, G., Li, J.; Liu, J.*, Emerging lipidome patterns associated with marine Emiliania huxleyi-virus model system. Sci. Total Environ. 2019, 688, 521-528. 

12. Zeng, J.#, Wang, Z. C.#, Huang, X., Eckstein, S. S., Lin, X. H., Piao, H. L., Weigert, C., Yin, P. Y., Lehmann, R.*, Xu, G. W.*, Comprehensive Profiling by Non-targeted Stable Isotope Tracing Capillary Electrophoresis-Mass Spectrometry: A New Tool Complementing Metabolomic Analyses of Polar Metabolites. Chem. Eur. J. 2019, 25 (21), 5427-5432. 

13. Tang, L.#, Zeng, J.#, Geng, P. Y., Fang, C. N., Wang, Y., Sun, M. J., Wang, C. S., Wang, J., Yin, P. Y., Hu, C. X., Guo, L., Yu, J. E., Gao, P., Li, E. Y., Zhuang, Z. P., Xu, G. W.*, Liu, Y.*, Global Metabolic Profiling Identifies a Pivotal Role of Proline and Hydroxyproline Metabolism in Supporting Hypoxic Response in Hepatocellular Carcinoma. Clin. Cancer Res. 2018, 24 (2), 474-485. 

14. Huang, X.#, Zeng, J.#, Zhou, L. N., Hu, C. X., Yin, P. Y.*, Lin, X. H.*, A New Strategy for Analyzing Time-Series Data Using Dynamic Networks: Identifying Prospective Biomarkers of Hepatocellular Carcinoma. Sci. Rep. 2016, 6. 

15. Zeng, J., Huang, X., Zhou, L., Tan, Y., Hu, C., Wang, X., Niu, J., Wang, H., Lin, X.*, Yin, P.*, Metabolomics Identifies Biomarker Pattern for Early Diagnosis of Hepatocellular Carcinoma: from Diethylnitrosamine Treated Rats to Patients. Sci. Rep. 2015, 5, 16101. 

16. Zeng, J.#, Yin, P.#, Tan, Y., Dong, L., Hu, C., Huang, Q., Lu, X., Wang, H.*, Xu, G.*, Metabolomics Study of Hepatocellular Carcinoma: Discovery and Validation of Serum Potential Biomarkers by Using Capillary Electrophoresis-Mass Spectrometry. J. Proteome Res. 2014, 13 (7), 3420-3431. 

17. Zeng, J., Kuang, H., Hu, C. X., Shi, X. Z., Yan, M., Xu, L. G., Wang, L. B., Xu, C. L.*; Xu, G. W.*, Effect of Bisphenol A on Rat Metabolic Profiling Studied by Using Capillary Electrophoresis Time-of-Flight Mass Spectrometry.Environ. Sci. Technol. 2013, 47 (13), 7457-7465. 

代表性专利/软件著作权

1. 曾珺,钟月,鄢庆枇,一种用于判断斜带石斑鱼内脏白点病致病菌基因改造作用的联合型代谢标志物及检测试剂盒,ZL202111152959.3

2. Jun Zeng, Yue Zhong, Xinyu Han, Zhiqiang Yang, Jingwen Hao, Guangming Liu, COMBINED METABOLIC MARKER FOR JUDGING EFFECT OF ALLERGEN OF AQUATIC PRODUCT BASED ON DENDRITIC CELLS AS WELL AS USE AND DETECTION KIT THEREOF, LU502273

3. 许国旺,曾珺,尹沛源,孔宏伟,一种用于诊断肝癌的联合型代谢标志物及其检测试剂盒,ZL201410206533.5

4. 许国旺,曾珺,陈俊,尹沛源,基于稳定同位素标记辅助的代谢组学研究分析器软件[简称:SIAM Analyzer]V1.02016SR363638

5. 林树海,陈亮生,曾珺,谢龙旭,基于质谱的心磷脂定性软件[简称:心磷脂定性软件]V1.02023SR1486433

代表性获奖

1. 3rd IUPAC International Congress on Analytical Sciences 2017, Best Poster Award, 2017

2. 第三届全国质谱分析学术报告会,优秀墙报奖,2017

3. 厦门市科学技术进步奖,二等奖(排名7),2020

4. 岛津奖学金,2016

人才培养

第八届全国大学生生命科学竞赛(科学探究类)

全国三等奖,福建省二等奖,2023年,指导教师

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