姓名  李志朋

职称：  副教授

性别：   男

毕业院校：厦门大学化学化工学院

学历： 研究生

学位： 博士

所在单位： 集美大学

入职时间：2019.4

职务：  无

学科：  生物工程、食品科学与工程

办公地点： 灿英511

通讯地址：厦门集美区印斗路43号

E-mail: lzp2019@jmu.edu.cn

个人简介

李志朋，工学博士，硕导，主要从事微生物来源的新型食品营养添加剂及其合成过程的代谢改造的研究，食品胶体废弃物资源化利用。研究的重点是开发基因工程技术（基因编辑）、代谢组学、转录组学、定向自适应性驯化技术、发酵技术，分析微生物发酵代谢机制，合成目标产品。近五年以来，发表SCI论文60余篇，其中第一作者（或通讯作者）30余篇，JCR-Q1的17篇，JCR-Q2 的11篇；公开发表国家专利13项，授权8项。主持6项国家级和省部级项目，作为学术骨干参与国家重点/重大专项/面上项目等国家级项目6项。

曾获2021-2022集美大学优秀班主任；指导学生参加“萌番姬杯”国际大学生农业创新创业大赛获“优秀创业团队”（国赛）,福建省生命科学竞赛三等奖，互联网+福建省赛区银奖，中国国际大学生创新大赛（原互联网+）国赛/省赛金奖。

教育经历

（1）2014-9至2019-3, 厦门大学, 生物化工, 博士, 导师: 何宁

（2） 2010-9至2013-6, 厦门大学, 海洋生物学, 硕士, 导师: 焦念志（院士）

（3）2006-9至2010-6, 内蒙古师范大学, 生态学, 学士

工作经历

（1）2019-4至今, 集美大学, 食品与生物工程学院, 讲师，副教授

（2）2020-4至2021年5月，厦门市海洋发展局，干部挂职

社会兼职

福建省化工学会 监事；

福建省生物工程学会 理事；

Frontiers in Sustainable Food(IF=5.005)客座主编；

《食品研究与开发》 青年编委；

iMeta青年编委；

2019-2024年度福建省科技特派员。

研究方向

微生物源食品营养添加剂

食品胶体工业废弃物的资源化利用

代表性科研项目

1. 虾青素和油脂合成途径在裂殖壶菌中耦合调控机制研究，厦门市自然科学基金面上项目（3502Z202473054），2024.7-2027.6，8万元，主持/在研。

2. 红藻胶产品氯酸盐消减控制技术研发与产品创新，国家重点研发计划“食品制造与农产品物流科技支撑”重点专项子课题（2023YFD2100603-02），2023.12-2026.11，80万元，主持/在研。

3. 基于CRISPRCas9基因编辑和代谢组学研究法夫酵母虾青素合成的“双环和单环”途径，国家自然科学基金，项目代码 32001672，起止年月2021.01-2023.12。主持/结题。

4. 自适应性耦合驯化结合代谢组学探究法夫酵母合成虾青素的代谢机制，福建省自然科学基金，项目代码2020J01678，起止年月2020.11-2023.11。主持/结题。

5. 自适应性驯化法夫酵母合成虾青素，福建省教育厅，项目代码JAT190339，起止年月2020.1-2023.10。主持/结题。

6. 微生物发酵海藻胶制备海藻寡糖的工艺研发，福建省重点实验室开放基金，项目代码Z820266，起止年月2020.5-2021.1。主持/结题。

7. 生物反应工程（2021思政教改精品项目），集美大学思政教改项目。项目代码C150506，起止年月2021.10-2023.10。主持/结题。

代表性科研论文

（1）Boyan Duan, Yanyan Wu, Shanyu Xie, Tao Hong, Yuanfan Yang, Mingjing Zheng, Zedong Jiang, Yanbing Zhu, Qingbiao Li, Hui Ni, Yuanpeng Wang, Xiping Du*, Zhipeng Li*. Antifungal mechanism and application to phytopathogenic fungi after anaerobic fermentation of Gracilaria agar wastewater[J]. Bioresource Technology, 2025, 416 131818-131818.

（2）Xiping Du, Xiaochen Chen, Liang Chen, Yuanfan Yang, Hui Ni, Qingbiao Li, Zhipeng Li*, Zedong Jiang*. Tyrosinase inhibition mechanism of polyphenols from Porphyra haitanensis extracted by cyclic subzero temperature[J]. Algal Research, 2025, 86 103943-103943.

（3）Zhipeng Li, Li You, Xiping Du, Haoyi Yang, Liang Yang, Yanbing Zhu, Lijun Li, Zedong Jiang, Qingbiao Li, Ning He*, Rui Lin, Zhen Chen, Hui Ni. New strategies to study in depth the metabolic mechanism of astaxanthin biosynthesis in Phaffia rhodozyma.[J]. Critical reviews in biotechnology, 2024, 45 (2): 11-19.

（4）Yuanzhen Song, Haoyi Yang, Li You, Qingbiao Li, Hui Ni, Xiping Du, Yanbing Zhu, Lijun Li, Zedong Jiang, Mingjing Zheng, Zhipeng Li*. Mechanism of melatonin and sodium orthovanadate regulating astaxanthin biosynthesis in Phaffia rhodozyma[J]. Industrial Crops & Products, 2024, 218 119011-119011.

（5）Xianze Luo, Yanyan Wu, Shuhe Wang, Zhu Xiong, Xiping Du, Mingjing Zheng, Yanbing Zhu, Zedong Jiang, Qingbiao Li, Hui Ni, Zhipeng Li*, Zhaohua Chen. Frontier review of key reduction technologies and resource utilization of waste during the seaweed gel production process[J]. Blue Biotechnology, 2024, 1 (1): 12-12.

（6）Wu Yanyan, Duan Boyan, Lin Qiaoyan, Liang Yingying, Du Xiping, Zheng Mingjing, Zhu Yanbing, Jiang Zedong, Li Qingbiao, Ni Hui*, Li Zhipeng*, Chen Jinfang. Fermentation of waste water from agar processing with Bacillus subtilis by metabolomic analysis.[J]. Applied microbiology and biotechnology, 2024, 108 (1): 11-15.

（7）Zhen Chen, Menglei Wang, Yanyan Wu, Juzhong Tan, Zhipeng Li*. Editorial: High value utilization of waste in food processing[J]. Frontiers in Sustainable Food Systems, 2024, 8

（8）Juan Wang, Yanbing Zhu, Zedong Jiang, Xiping Du, Mingjing Zheng, Lijun Li, Hui Ni, Yuanpeng Wang, Zhipeng Li*, Qingbiao Li. Characteristics and mechanism of Ni2+ and Cd2+ adsorption by recovered perlite from agar extraction residue[J]. Chinese Journal of Chemical Engineering, 2024, 72 141-152.

（9）Xuehua Han, Xin Wang, Yanhong Chen, Yuanfan Yang, Xiping Du*, Zhipeng Li*, Zedong Jiang, Hui Ni, Qingbiao Li. Optimized separation of astaxanthin stereoisomers from microbial sources using chiral HPLC.[J]. Analytical methods : advancing methods and applications, 2024,

（10）Shanyu Xie, shuai zhong, juan Wang, jinfang chen b, Lijun Li , Xiping Du, Tao Hong, Mingjing Zheng, Yanbing zhu, Wei Yins, Qingbiao Li, HuiNi*, Zhipeng Li*, Recovery of alkali in Gracilaria agarproduction by electrodialysis andmembrane concentration, Algal Research, 2024：103485

（11）Xiaochen Chen, Yating Xu, Xiping Du*, Zhipeng Li*, Yuanfan Yang, Zedong Jiang, Hui Ni, Qingbiao Li,Effect of Porphyra haitanensis polyphenols from different harvest periods on hypoglycaemic activity based on in vitro digestion and widely targeted metabolomic analysis, Food Chemistry, 2024,437-137793

（12）Yanyan Wu, Boyan Duan, Qiaoyan Lin, Yingying Liang, Xiping Du, Mingjing Zheng, Yanbing Zhu, Zedong Jiang, Qingbiao Li, Hui Ni, Zhipeng Li*, Jinfang Chen*, Fermentation of waste water from agar processing with Bacillus subtilis by metabolomic analysis, Applied Microbiology and Biotechnology, 2024,108:15.

（13）Zhipeng Li, Juan Wang, Jinfang Chen, Yi Liang, Shanyu Xie, Qingbiao Li, Xiping Du, Zedong Jiang, Yanbing Zhu, Hui Ni,Characteristics and mechanisms of sustainable recovery of perlite from carrageenan residue by green technology and its application in carrageenan extraction, Journal of Cleaner Production, 2024, 434:140131.

（14）Boyan Duan, Canwei Ling, Xin Wang, Qiaoyan Lin, Zedong Jiang, Yanbing Zhu, Qingbiao Li, Hui Ni, Yuanpeng Wang, Xiping Du*, Zhipeng Li*, Anaerobic fermentation of carrageenan waste residue to obtain antifungalactivity,Process Biochemistry,2024,136:128-135.

（15）Haoyi Yang, Liang Yang, Xiping Du, Ning He, Zedong Jiang*, Yanbing Zhu, Lijun Li, Hui Ni, Qingbiao Li, Zhipeng Li*, Metabolomics of astaxanthin biosynthesis and corresponding regulation strategies in Phaffia rhodozyma, Yeast,2023,40:254-264.

（16）Liang Yang, Hao-Yi Yang, Li You, Hui Ni, Ze-Dong Jiang, Xi-Ping Du, Yan-Bing Zhu, Ming-Jing Zheng, Li-Jun Li, Rui Lin, Zhi-Peng Li*, Qing-Biao Li*, Transcriptomics analysis and fed-batch regulation of high astaxanthin producing Phaffia rhodozyma/Xanthophyllomyces dendrorhous obtained through adaptive laboratory evolution, Journal of Industrial Microbiology & Biotechnology,2023,50:1.

（17）Xin Wang, Gaoping Chang, Yating Xu, Zhipeng Li*, Xiping Du*,Yuanfan Yang, Zedong Jiang, Hui Ni, Qingbiao Li ,Effect of phytol isolated from edible red alga (Bangia fusco-purpurea) on tyrosinase inhibition and its application on food preservation, LWT, 2023, 185-115146

（18）Zhipeng Li, Yuting Dong, Yifei Zhang, Mingjing Zheng, Zedong Jiang*, Yanbing Zhu, Qingbiao Li, Shanggui Deng, Hui Ni*, Lactobacillus-fermentation enhances nutritional value and improves the inhibition on pancreatic lipase and oral pathogens of edible red seaweed Bangia fusco-purpurea, LWT-Food Science and Technology, 2023,179:114643

（19）Zhipeng Li, Du Zeping, Li Hebin, Chen Yanhong, Zheng Mingjing, Jiang Zedong, Du Xiping, Ni Hui, Zhu Yanbing*. Characterisation of marine bacterium Microbulbifer sp. ALW1 with Laminaria japonica degradation capability，AMB Express, 2022,12(1)

（20）Xin Wang, Tao Zhang, Xiaochen Chen, Yating Xu, Zhipeng Li*, Yuanfan Yang, Xiping Du*, Zedong Jiang, Hui Ni, Simultaneous Inhibitory Effects of All-Trans Astaxanthin on Acetylcholinesterase and Oxidative Stress,Mar. Drugs, 2022, 20:247.

（21）Zhipeng Li，Qing-song Hu, Jin-fang Chen, Xue Liu, Yu-yan Sang, Juan Wang, Ming-jing Zheng, Hui Ni, Qing-biao Li, Zedong Jiang* ,Yan-bing Zhu*, Optimized strategy for simultaneous recovering bioactive oligosaccharides and reusable perlite from agar industrial waste residues, Journal of Cleaner Production, 2022 378(4):134631

（22）Zhipeng Li，Huang Xiaoyi, Guo Yuxi, Zhang Chenghao, Yang Liang, Du Xiping, Ni Hui, Wang Xuchu, Zhu Yanbing*,，Toward Understanding the Alginate Catabolism in Microbulbifer sp. ALW1 by Proteomics Profiling. Frontiers in Bioengineering and Biotechnolog，2022，10：829428

（23）Zhipeng Li, Haoyi Yang, Chenhua Zheng, Xiping Du, Hui Ni, Ning He, Liang Yang, Li You, Yanbing Zhu and Lijun Li*，Effectively Improve the Astaxanthin Production by Combined Additives Regulating Different Metabolic Nodes in Phaffia rhodozyma, Frontiers in Bioengineering and Biotechnolog，2022，9：812309

（24）Zhipeng Li，Chen Lina，Yang Haoyi，Li Tianli，Du, Xiping，He Ning，Jiang Zedong，Li Lijun，Ni Hui， The role of key genes in astaxanthin biosynthesis in Phaffia rhodozyma by transcript level and gene knockout，Process biochemistry，2022，113：158-166.

（25）Zhipeng Li，Tong Meng，WeiHang，Xingyu Cao，Hui Ni，Yanyan Shi，Qingbiao Li，Yuyan Xiong，Ning He，Regulation of glucose and glycerol for production of docosahexaenoic acid in Schizochytrium limacinum SR21 with metabolomics analysis，Algal Research，2021，58：102415

（26）Zhipeng Li, Xueping Ling, Hao Zhou, Tong Meng, Jinjin Zeng, Wei Hang, Yanyan Shi and Ning He* Screening chemical modulators of benzoic acid derivatives to improve lipid accumulation in Schizochytrium limacinum SR21 with metabolomics analysis. 2019. Biotechnology for Biofuels. 12:209-219

（27）Zhipeng Li, Tong Meng, Xueping Ling, Jun Li, Chuqiang Zheng, Yanyan Shi, Zhen Chen, Zhenqi Li, Qingbiao Li, Yinghua Lu, Ning He*, Overexpression of malonyl CoA-acyl transacylase in Schizochytrium sp.: metabolomics analysis and polyunsaturated fatty acid accumulation improvement, Journal of Agriculture and food chemistry, 2018,66(21):5382-5391  

（28）Zhipeng Li, Zhen Chen, Hong Ye, Yuanpeng Wang, Weiang Luo, Jo-Shu Chang, Qingbiao Li, Ning He*, Anaerobic co-digestion of sewage sludge and food waste for hydrogen and VFA production with microbial community analysis. Waste management, 2018, 78: 789-799.  

（29）Zhipeng Li, Xi Chen, Jun Li, Tong Meng, Lingwei Wang, Zhen Chen, Yanyan Shi, Xueping Ling*, Weiang Luo, Dafeng Liang, Yinghua Lu, Qingbiao Li, Ning He*; Functions of PKS genes in lipid synthesis of Schizochytrium sp. by gene disruption and metabolomics analysis. Marine Biotechnology, 2018, 20(6): 792-802.

代表性专利

李志朋, 杨亮, 李清彪, 杨昊翌, 姜泽东, 倪辉, 朱艳冰, 杜希萍, 郑明静. 一种法夫酵母代谢产物的分析方法[P]. 福建省: ZL114720618B, 2024-12-03.

李志朋, 凌灿伟, 杜希萍, 李清彪, 陈昭华, 杨远帆, 陈艳红, 伍菱, 郑明静, 姜泽东, 朱艳冰, 胡阳, 何凡, 李利君, 倪辉. 一种利用离子液体提取琼脂工业废液中多酚的方法及其应用[P]. 福建省: ZL115403634B, 2024-12-20.

李志朋; 林巧燕; 杜希萍; 姜泽东; 朱艳冰; 郑明静; 杨远帆; 洪涛; 李清彪; 倪辉; 一种利用海藻胶废液制备抗菌物质的方法[P]. 中国,ZL202311099824.4,2023-09-04.

李志朋； 凌灿伟; 杜希萍; 许雅婷; 陈艳红; 杨远帆; 倪辉; 姜泽东; 郑明静; 朱艳冰; 胡阳; 李利君; 何凡; 一种从琼脂生产废液中回收制备抗菌剂的方法[P]. 中国：ZL2022 1 0254328.0,2022-03-15.

李志朋; 梁懿; 陈锦芳; 谢杉玉; 姜泽东; 朱艳冰; 倪辉; 李清彪; 一种从卡拉胶残渣中回收利用珍珠岩的方法[P]. 中国：ZL 202110666238.8, 2022-10-25.

何宁; 李志朋; 一种酮基合成酶基因敲除的裂殖壶菌工程菌的构建方法及其应用,2020-1-17, 中国, ZL201710078025.7.

何宁; 李志朋; 陈震; 一种脱氢异构酶基因敲除的裂殖壶菌工程菌的构建方法及其应用, 2020-1-17, 中国, ZL201710077962.0.

何宁; 孟彤; 李志朋; 一种促进裂殖壶菌产油脂的方法, 2020-7-6, 中国, ZL201710548502.1.

代表性获奖成果

“余虾成琦”-虾青素Q糖，获得“萌番姬杯”国际大学生农业创新创业大赛获“优秀创业团队”，互联网+省赛 银奖，中国国际大学生创新大赛国赛 金奖。